Wednesday, April 10, 2013

 

Meet Terrence J. Sejnowski



Image of Candidate Terrence J. Sejnowski *78Terrence J. Sejnowski *78 
San Diego, CA
 

Graduate Alumni

 
A pioneer in the field of computational neuroscience and regarded by many as the world’s foremost theoretical brain scientist, Terrence J. Sejnowski has devoted much of his life to gaining a deeper understanding of the brain mechanisms underlying behavior. He has done groundbreaking work.
 
Sejnowski is the Francis Crick Chair at the Salk Institute for Biological Studies, where he directs the Computational Neurobiology Laboratory and is an Investigator with the Howard Hughes Medical Institute. He is one of only ten living people to be a member of the National Academy of Sciences, the National Academy of Engineering and the Institute of Medicine.
 
Known as the founder of the science of neural computation that combines the principles of physics, computer science, and neural modeling to studying behavior and the brain, Sejnowski is particularly interested in the hippocampus, which is believed to play a key role in learning and memory, and the cerebral cortex. His laboratory uses experimental and modeling techniques to gain information about how the human brain is capable of learning and storing memories. This research may eventually provide clues to combating Alzheimer's disease and other disorders that affect the ability to remember faces, names, places, and events.
 
Sejnowski has over 500 scientific publications and several books to his credit, including The Computational Brain, a best-selling textbook at MIT Press, and Liars, Lovers and Heroes, a trade book about how the brain works.
 
A graduate of Case Western Reserve, Sejnowski went to Princeton to study General Relativity with legendary physicist John Wheeler, earning his MA in 1970 and his PhD in 1978. He points out, though, "Princeton gave me the freedom to explore other interests, and I took courses in biology, psychology, and history of science, which strongly influenced my career." A mentor in the physics department encouraged him to pursue his burgeoning interest in biology.
 
"My first faculty position was in the Biophysics Department at the Johns Hopkins University, where I pioneered the field of neural networks, which was a new type of computer based on the architecture of the brain," he says. His computer program, called NETtalk, "learned how to pronounce English words, which I demonstrated on the Today Show." He says much of the technology for things like noise cancellation in cell phones and facial expression recognition originated from research from his lab.
 
Sejnowski founded Neural Computation, which is a prominent research journal. He is also the President of the Neural Information Processing Systems (NIPS) Foundation, "which organizes the largest annual machine learning conference. This field is important for many industries that rely on big data, including search engines at Google and Microsoft and recommendation systems at Amazon and Netflix."
 
He also serves on the Advisory Board of the Searle Scholars Program, which funds research of young scientists, and on the Research Council for the State University of New York, as well as scientific advisory boards of Syntaptics, Illumina, the Gulbenkian Foundation, and others. Sejnowski has a long list of awards and honors, including the Wright Prize for interdisciplinary research from Harvey Mudd College, the Hebb Prize, and the Neural Pioneer Award from the Institute of Electrical and Electronics Engineers.
 
Sejnowski has worked with many students over the years and is listed as the most connected neuroscientist at neurotree.org, which keeps track of mentors and students, and he remains close with members of Princeton’s Physics faculty. "I highly value my colleagues at the Princeton Neuroscience Institute, which is at the forefront of a new era in neuroscience research that will lead to a deeper understanding of the brain and behavior."

Wednesday, January 09, 2013

 

Twenty-Teen's are Here with 2013

2013 should be a good year for Missing Lymph, as all years have been good since I regrew my tonsils unintentionally.  I have been wanting to tell you about the multivitamin I take -- I have not been following any rejuvenation regimes lately, maybe in 2013 I'll give it a go again to see what results I get.    My multivitamin is from Vitamin World, recommended, a big I like it on Facebook -- and it is called ULTRA WOMAN. [I like the Marvel sounding quality of it! ]  I take half of the recommended dose of two caplets.

Also, a fellow Princeton alumna, has big news for the world of science:

I recently started a science communications company called www.c3science.com
 We specialize in helping scientists, particularly young and  mid-career scientists, get funded and get their work out. But we also enjoy working with seasoned scientists as well. I would appreciate it if you would spread the word to people you know who need high-quality science editing and writing, proposal/grant writing, and other communication services. 
www.c3science.com
www.lesliebienen.com
www.climateconservation.org

Tuesday, August 28, 2012

 

My fortune cookie today said:

"You could prosper in the field of medicine." :) I could.

Wednesday, February 08, 2012

 

"Creativity in Neuroscience" by Dr. Bruce Perry

Creativity In Neuroscience

Dr. Bruce Perry
Child Trauma Academy/ Houston, Texas
Author of Born For Love and
The Boy Who Was Raised as a Dog.

General Public Presentation
with Question and Answer Session

7 - 9 p.m.
Thursday, March 1, 2012
Conference Center - Preston Ridge Campus
9700 Wade Boulevard, Frisco

Monday, January 02, 2012

 

Entering the Seventh Year

I would say I am moving at a snail's pace.  My friends the snails would say "it is difficult work you are trying there".  2012 marks Missing Lymph's seventh year.  Dry Toast with 7Up!   Call 007.  Does my week need ten days instead of seven?

Saturday, December 31, 2011

 

Rx for Nutritional Healing Pages 750 -752

Prescription for Nutritional Healing, copyright Phyllis A. Balch, CNC (1930-2004) and her estate, is a sizable work, too bad it is missing an index of herbs, supplements, and foods recommended by the author.  For Missing Lymph, the key pages are 750 thru 752.

Page 752; "In the past, doctors removed tonsils on a very frequent basis. Today we know that the tonsils are important for the proper functioning of the immune system."

Saturday, March 04, 2006

 

Tonsils Grow Back

Something tells me it's time to revisit, and post, the substances that made my tonsils grow back thirty-three years after my tonsillectomy. A good friend had recommended Strivectin to combat stretch marks, I made a note to myself to look it up on the Web. What I found was the Fitness First USA "Anti-Wrinkle/Anti-Inflammation" kit, which not only offered the Strivectin, but ingestible capsules of (1) Co-Enzyme Q 10, (2) Alpha Lipoic Acid and (3) Acetyl-L-Carnitine. I researched each one and decided to embark in the regimen recommended by Fitness First USA.

Two weeks later, I could feel my tonsils growing back.

Friday, February 03, 2006

 

Puerto Rico Tonsillectomy Awareness Community

Taking the advice of a very good friend, the Puerto Rico Tonsillectomy Awareness Community (PRTAC) blog has been born. It will serve as a place to reach out to people who have been tonsillectomized to become aware of the possible consequences of their surgery. I wrote this description for it:
"Multiple sclerosis (MS) is considered a neurological disease caused by lymph. I
believe lymph adds power to the nervous system because in MS it takes power
away. A tonsillectomy removes a gland that contains and transports lymph at the
base of the throat. So, a tonsillectomy, in order to correct an immunological
condition, creates a long-term one in neurological terms. -- Frances M. Pabon,
Founder, PRTAC

Godspeed PRTAC!

Wednesday, November 16, 2005

 

Lymph flowing thru tonsils has its own biological age

With the uncritical attention of a Princeton friend and blogfather, I was able to sort this out (knowing it sounds very crazy or like a piece of science fiction) in my mind. Now I have the courage to write it here: the lymph that flows thru my newly regrown tonsils seems have the chronological age I had when I was tonsillectomized.

So, although I'm forty years of chronological age, the lymph that flows thru my tonsils is the age I was when I was tonsillectomized: 5. I can feel that age, my voice goes back that age when I'm calm, relaxed and unaware of myself, certain spots of my skin and hair show that age too.

Most importantly, aside from my personal situation now, when scientists make this discovery, it's going to change medicine forever.

Tuesday, August 30, 2005

 

Silent Neurological Deficit

Chatting with a woman in her sixties, who had been tonsillectomized and had most of her thyroid gland removed, the concept that a tonsillectomy creates a neurological deficit later in life occurred to me as the simplest way to explain Missing Lymph's motivation.

Friday, August 19, 2005

 

My biceps and triceps

Both my biceps and triceps seem to work better together now, as if linked by a stronger bond than before.

Wednesday, June 29, 2005

 

Something is happening to my eyebrows

My eyebrows seem to be regaining lymph lost w. my tonsillectomy, I need to take a photo to show you. Also, my Princeton friend Christian Crumlish knows that after my spinal cord regained what I refer to as a "lymphatic flow" I have slowly regained a new feeling throughout my back, radiating gently from both sides of my spinal cord and flowing towards the front of me.

Friday, June 10, 2005

 

Before and After Regrowing my Tonsils


This morning, washing my hair, I noticed my head is getting smaller! Posted by Hello

Saturday, May 21, 2005

 

Lymph Flows 2.0: Update

I've passed the one-year anniversary of the first sign of tonsil regrowth. I marked the day quietly with this posting (among two others less related to Missing Lymph) @ Good Bloggin' , my personal web-based diary in which I write almost daily.

Why I don't write here more often? Because it's painful. My progress in what I refer to as a "re-tonsillation" leading to "lymphatic renewal" is very personal, many times I've felt sick as I feel my tonsils @ the back of my head lymphatically try to reach every point of my body, and fail. It seems that slowly, the network that was disrupted by my tonsillectomy is being rebuilt but in the meantime, I feel some lymphatically "dead" spots -- on my right cheek, on the sides of my chest, @ the front of my legs, my entire back...

Where does my lymph flow now?
  1. Through my skull, from the back to the front of my head.
  2. Through my lungs, I think I've recovered "lymphatic breathing" straight up from my diaphragm.
  3. Through my bone marrow, I feel it inside the heels of my feet if I concentrate serenely.
  4. Up to the surface of my head, I've continued to lose chunks of hair, falling out as if the lymph there is pushing them out, new hair is the replacement, finer, lustrous and simply prettier.

Do I have stronger allies now in my quest to scientifically prove my re-tonsillation? I do, I just don't feel free to publicly disclose their names.

Please, read "Avanti del Suo Tempo" another Missing Lymph-related Good Bloggin' posting, which shows exactly the kinds of people who would be my strongest allies.


Thursday, April 07, 2005

 

Lymph Flows 1.4.1: Healing Faster

The blister I was healing is finally unnoticeable today. So, eight days after I hurt myself walking in the wrong shoes, my skin has completely healed itself. I wish I could check a "healing" guidelines chart to see how my healing time compares to someone my same age/gender.

Monday, April 04, 2005

 

Milestone 1.0: Groundbreaking survey results

The first milestone in my efforts to advocate for research into the long-term effects of tonsillectomies is reporting the results of the groundbreaking survey I conducted. The survey was purposefully short to gauge if any differences would arise when comparing tonsillectomized adults with their "tonsils-intact" counterparts. The areas of comparison were:

1. Overall Health
2. Physical Activity
3. Vision
4. Hearing
5. Dental Health
6. Health Conditions

Fifty-three people participated, of which:

24 were tonsillectomized, 23 during childhood and one in adulthood.
29 were "tonsils-intact"

The average age of all participants was: 40.6 years old.

Participants were asked to rate themselves on a purposefully positive scale from 10 (= Excellent) to 0 (= Poor) in each of the five dimensions (Overall Health, Physical Activity, Vision, Hearing and Dental Health).

One “Yes or No” question inquired about “health conditions” which participants who answered affirmatively could then use to report any conditions they chose.

The following data table compares the average results of the entire sample to the tonsillectomized and "control" (tonsils-intact) groups:

NAgeHealthPhysical ActivityVisionHearingDental
All5340.68.086.645.817.977.31
T-group2443.17.986.585.258.007.17
Control2938.18.176.696.387.937.45

Saturday, April 02, 2005

 

Lymph Flows 1.5: What is optimal lymph?

After my poisoning crisis, I need to post this for you too. I'd like to know: (1) what is optimal lymph? and (2) *who* has optimal lymph? Why not compare a healthy laboratory animal (animal testing may be needed here folks, unless we experiment on human guinea pigs) to one who has been force-fed, say, a Diet Pepsi! (I doubt there is any laboratory animal that would voluntarily drink a Diet Pepsi, unless it was completely parched but I may be wrong).

I can picture a small laboratory mouse getting violently sick as I did, in a cruel experiment on the animal, which makes me lean towards using either:

(1) myself as a human guinea pig or (2) a group of healthy vegetarian, vegan or normally non-Diet Pepsi drinking folks to form a human guinea group.

Right now, I'm not ready to drink a Diet Pepsi ever again -- but if I absolutely have to, I will.

To all of you: I hope you are drinking water, milk, soy milk, natural fruit juice or herbal teas... *not* any toxic sodas.

Thursday, March 31, 2005

 

Lymph Flows 1.4: Healing Faster

What if your body cut back the time it took to heal noticeably? Mine has since my tonsils re-grew; cuts, bruises, blisters and burns heal much faster than before. Which makes me wonder: how does lymphatic fluid promote cell repair and how did my body heal itself before, when I didn't have tonsils?

The current wound I'm healing: a blister on my foot from walking in the wrong pair of shoes w. my husband.

My challenge: how to bring my rapid healing to the attention of the right scientists, any suggestions?

Monday, March 21, 2005

 

Lymph Flows 1.3: Look @ my nails & check out my hair

Is this a women's beauty commercial? No, this is the third in the "Lymph Flows" series I started to report how my life is different as I live it with tonsils. As many of you know, I regrew my tonsils accidentally and now I'm convinced lymph is more than science currently knows. Today, I'll tell you about my new nails and hair, both which became markedly different after my tonsils regrew.

This is the first time I discuss with you results other than neurological of my tonsil regrowth - I'd categorize these results as dermatological. I hope my efforts bring attention from the world of dermatology to how lymph may interact with skin, hair and nails.

1. Nails:

Before: Sometimes bitten, dry and brittle
Now: Prettier, stronger yet pliant, nails. My pinky finger on my right hand seems to have acquired a life of its own, growing the smallest of measurements longer than the one on my left. Underneath that right, pinky finger nail, that the skin looks healthier (i.e. rosier) than the others. I suspect that slowly, my body is going to make all my nails look just like that one. My fingertips, especially of the right pinky, seem to have increased sensitivity, as if I could be the type of person that could sense with her fingertips the smallest of, say, tumors.

2. Hair:

Before: Breaking off easily and very fine, after my "palatine" tonsils (the ones that were removed and the last ones to become noticeable -- after my sublingual and nasopharyngeal ones were "reactivated" by my cell renewal regimen) were more noticeably back in working order, my old head of hair has slowly fallen off, to make way for my new hair.
Now: Thicker and shiny, I believe eventually, my hair will reach a new balance that includes the lymph that must flow in micro-amounts to my scalp. I can sense now that my hair follicles seem to have gotten deeper, and if by mistake I pull out some of my hair, it hurts a lot more than it did before.

I'd like to suggest another study based on my new nails and hair: how do the hair and nails of tonsillectomized people differ from the hair and nails of their "tonsils-intact" counterparts?

You may wonder if I show benefits to my skin: I do, my skin has become more supple but I suspect I have not shed all the pre-tonsils/lymph-deprived skin I had. The process is probably going to take awhile, I'm making sure that all the factors I do control (diet, exercise, rest, relaxation) are as close to optimal as I can muster (I get an "F" in exercise this past weekend but usually I'm pretty good!).

Friday, March 18, 2005

 

Lymph Flows 1.2: Stronger backbone

Hello to all the Venture Capitalists (VCs) who found this through Brain Waves.

This is second posting in a series I named "Lymph Flows" to discuss how regrowing my tonsils restored the flow of lymph to my head, in a very noticeable way, and seemed to re-energize my entire nervous system. The first, Lymph Flows 1.1, discussed how I'd reached my Missing Lymph tonsillectomy survey goal and how I enjoy helping people who want to know more about the possible long-term effects of their tonsillectomies and people who have contemplated having a tonsillectomy but are still entertaining other options.

Other Missing Lymph postings are:

1. A suggestion for all VCs to design a "tonsil implant" to be used by anyone who was tonsillectomized who is in serious lymphatic imbalance, to strengthen their nervous system and to improve their quality of life.

2. A listing of all the scientists with whom I've already communicated about my theory that lymph is "second to blood" in neurological ways currently unknown to science and medicine.

3. The first of a series of research questions I've thought of as a tonsillectomy research advocate, other questions include how do tonsillectomized mice differ from "tonsils-intact" counterparts.

Today, Lymph Flows is dedicated to my stronger backbone. As some of you may know, tonsils are located @ the sides of your throat, practically @ the top of your backbone. Ever since my tonsils re-grew, I've felt lymph flowing through my back, in a painless way, making me stronger and able to stand straighter (something I had always wondered about, I had a mini-dowager's hump noticeable on my 15th birthday, ten years after my tonsillectomy). A stonger backbone has also given me the most powerful lymphatic relaxation I have ever experienced. Now, on my yoga mat, I can focus on my backbone and how it relaxes every nerve ending of my body. I know that, without tonsils, my body had never relaxed as deeply, even though I'd been in excellent shape, doing Pilates with relaxation exercises frequently.

VCs around the world are invited to invest in research to prove that lymph adds power to the nervous system, and by the same token, it makes a nervous system much more capable of deep relaxation.

Friday, March 11, 2005

 

How does lymph influence neurogenesis?

Awhile ago, I made a mental note to post for you the numerous research questions that I can think of as a tonsillectomy research advocate. The first I'd like you to ponder is "how does lymph influence neurogenesis (neuron creation)?" The report that triggered my idea was about pioneering research carried out by Elizabeth Gould, a Princeton University professor. Here is the part of that article that struck me:

"... several important areas of the brain continue to create neurons throughout
life, a process called adult neurogenesis. In recent years, Gould has
investigated factors that influence the rate of adult neurogenesis and the roles
played by the new brain cells. ... recent studies examined neurogenesis in a
part of the brain called the hippocampus, which is involved in learning and
memory as well as in responding to stress. Previous studies had shown that
stress can significantly reduce neurogenesis."

Sunday, March 06, 2005

 

Meet the fMRI "Crew"

Tonsillectomy research advocacy will bring you to some of the brightest minds in science. I plan to present to you, one by one, all the outstanding scientists that I've "met" in my quest to spur scientific research into the long-term effects of tonsillectomies and in my quest to have science discover that lymph adds power to the nervous system and supports the brain making it more stable, happier, put-together and healthier overall.

Here's the list, in alphabetical order, and with sketchy details, of the first batch I've worked on:

Jonathan D. Cohen, Director, Center for the Study of the Mind and the Brain, Princeton University, Princeton, NJ: While Dr. Cohen is on sabbatical, someone else handled my email - I think my best route here is to recruit interested and somewhat renegade students to use tonsillectomies as research criteria!

Eric Connor, Johns Hopkins Univ., Baltimore, MD: I think my written eloquence fluctuates sometimes, the email I sent Dr. Connor is one of the best I've created putting "fingers to keyboard" rather than pen to paper! Yet, I think Dr. Connor's lab may not be set up for the kind of research I wrote to him about... dead end? Nah, I'm going to ask him if he knows someone else @ Hopkins who may be set up to run tests on tonsillectomized folks...

Lutz Jaencke, Germany: Has shown great kindness when replying to my inquiry. An email I wrote to him equated researching lymph beyond immunology to declaring the earth is round when everyone else considered it flat!

Wolf Singer, Director, Max-Planck-Institute for Brain Research, Germany: We are talking neurological research royalty here, wish me luck not getting bounced out of the virtual door!

Thomas Metzinger, Max-Planck-Institute for Brain Research, Germany: Same as above

Filippi Massimo, Italy: Dr. Massimo "heard" my request and asked me to be patient, it takes time to make things happen in science.

Osaka, Japan: Dr. Osaka utlized fMRI technology to publish a paper which I am having trouble finding for you right this minute but which I hope to find eventually to quote for you!
Whew! If any of you would like to volunteer to lobby these or any other scientists, let me know!

Wednesday, March 02, 2005

 

Lymph Flows 1.1: Tonsillectomy survey goal reached

As some of you know, regrowing my tonsils restored the flow of lymph to my head and restored part of me to how I was just before my tonsils were removed. If you'd like to know what happened, email me, please, because at this time the story is still too personal to share with people I don't know in an open forum like this one. Instead, I've begun a "Lymph Flows" work in progress as I report to you how my life is different now, as I live it with tonsils:

Today, completed Tonsillectomy Surveys #49 and #50 alighted to my delight in my emailbox @ TigerNet, Princeton's online alumni community. With #50 I've reached my goal, yet there are a few outstanding surveys people have promised to return which I hope to accommodate, so the sample size will exceed my goal.

I've also enjoyed being able to respond, with knowledge and practical advice, to people with concerns about their tonsils or their tonsillectomies. If my childhood dream of going to medical school still comes true, I'd become the first physician to regard her niche as "tonsillectomy reversal" and also the one to scientifically prove that lymph is "second to blood" in ways that are currently unknown to medicine.

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